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Article

STAT2*C related genotypes and allele but not TLR4 and CD40 gene polymorphisms are associated with higher susceptibility for asthma.

International journal of biological sciences - 1 Jan 2009

Hsieh Yao-Yuan, Wan Lei, Chang Chi-Chen, Tsai Chang-Hai, Tsai Fuu-Jen

Abstract excerpt

OBJECTIVE: Asthma is caused by a complex interaction between multiple genes and environmental factors. Herein we aimed to investigate whether signal transducer and activator of transcription (STAT2), toll-like receptors 4 (TLRs4) and CD40-related polymorphisms are associated with asthma susceptibility. DESIGN: Children were divided: (1) asthma (n=117); (2) normal controls (n=60). The polymorphisms of STAT2, TLR4...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 19159017
DOI: 10.7150/ijbs.5.74
PMCID: PMC2615545

Genes

STAT2
TLR4

Provenance

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