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Article

STAT4 gene polymorphisms in human diseases.

Frontiers in immunology - 1 Jan 2024

Xia Yan, Xie Yanni, Zhang Hao, Liu Lunzhi

Abstract excerpt

Signal transducer and activator of transcription 4 (STAT4) is a member of the STAT family, which is a group of transcription factors that regulate cytokine signaling. Genetic polymorphisms in STAT4 strongly influence immune responses and disease outcomes, especially in cancer and autoimmune diseases. Several studies have indicated that certain STAT4 gene variants are associated with alterations in STAT4...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39575235
DOI: 10.3389/fimmu.2024.1479418
PMCID: PMC11578735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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