Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

STAT6 - polymorphisms, haplotypes and epistasis in relation to atopy and asthma.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia - 1 Jun 2013

Godava Marek, Vrtel Radek, Vodicka Radek

Abstract excerpt

BACKGROUND: STAT6 has an important role in the IL-4 / IL-13 signalling pathway. Genome - wide association studies have shown that particular polymorphism (SNP) or haplotype variants of STAT6 as well as epigenetic gene modifications are associated with IgE level and asthma in childhood. METHODS: A review of the available literature was performed to map out the function and signalling pathway of STAT6, studies of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Epistasis, Genetic
Share to STAT6 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Haplotypes

Share to Immunoglobulin E

Share to Polymorphism, Single Nucleotide

Share to STAT6 Transcription Factor

Source

Identifiers

PMID: 23752766
DOI: 10.5507/bp.2013.043

Genes

STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

STAT6 - polymorphisms, haplotypes and epistasis in relation to atopy and asthma.PMID 23752766Read ↗

Association of a STAT 6 haplotype with elevated serum IgE levels in a population based cohort of white adults.Semantic proximity Read ↗

Association of STAT6 and ADAM33 single nucleotide polymorphisms with asthma bronchiale and IgE level and its possible epigenetic background.Semantic proximity Read ↗

An IgE-associated polymorphism in STAT6 alters NF-kappaB binding, STAT6 promoter activity, and mRNA expression.Semantic proximity Read ↗

STAT6 as an asthma candidate gene: polymorphism-screening, association and haplotype analysis in a Caucasian sib-pair study.Semantic proximity Read ↗

Association analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high serum IgE phenotypes.Semantic proximity Read ↗

Association of the STAT-6 rs324011 (C2892T) variant but not rs324015 (G2964A), with atopic asthma in a Saudi Arabian population.Semantic proximity Read ↗

REPORT-Association analysis of STAT6 SNP with asthma in Pakistani population.Semantic proximity Read ↗

Signal transducer and activator of transcription 6 haplotypes and asthma in the Indian population.Semantic proximity Read ↗

Association of STAT6 variants with asthma risk: a systematic review and meta-analysis.Semantic proximity Read ↗

Linkage and association studies of STAT6 gene polymorphisms and allergic diseases.Semantic proximity Read ↗

Variation in dinucleotide (GT) repeat sequence in the first exon of the <i>STAT6</i> gene is associated with atopic asthma and differentially regulates the promoter activity in vitroSemantic proximity Read ↗

STAT1 gene variations, IgE regulation and atopy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.