Article
Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans.
The Journal of clinical endocrinology and metabolism - 1 Jan 2008
Palmer Nicholette D, Lehtinen Allison B, Langefeld Carl D, Campbell Joel K, Haffner Steven M, Norris Jill M, Bergman Richard N, Goodarzi Mark O, Rotter Jerome I, Bowden Donald W
Abstract excerpt
CONTEXT: Genetic variation at the transcription factor 7-like 2 locus has been linked to type 2 diabetes in predominantly European-derived populations. The biological basis of these associations remains to be determined. OBJECTIVE: The objective of this study was to evaluate previously associated variants for association with measures of glucose homeostasis in Hispanic-Americans and African-Americans and...
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