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Article

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program.

The New England journal of medicine - 20 Jul 2006

Florez Jose C, Jablonski Kathleen A, Bayley Nick, Pollin Toni I, de Bakker Paul I W, Shuldiner Alan R, Knowler William C, Nathan David M, Altshuler David

Abstract excerpt

BACKGROUND: Common polymorphisms of the transcription factor 7-like 2 gene (TCF7L2) have recently been associated with type 2 diabetes. We examined whether the two most strongly associated variants (rs12255372 and rs7903146) predict the progression to diabetes in persons with impaired glucose tolerance who were enrolled in the Diabetes Prevention Program, in which lifestyle intervention or treatment with...

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Identifiers

PMID: 16855264
DOI: 10.1056/NEJMoa062418
PMCID: PMC1762036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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