Article
Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study.
Diabetes - 1 Apr 2008
Palmer Nicholette D, Goodarzi Mark O, Langefeld Carl D, Ziegler Julie, Norris Jill M, Haffner Steven M, Bryer-Ash Michael, Bergman Richard N, Wagenknecht Lynne E, Taylor Kent D, Rotter Jerome I, Bowden Donald W
Abstract excerpt
OBJECTIVE: Evaluate type 2 diabetes susceptibility variants identified from genome-wide association studies in Hispanic Americans and African Americans from the Insulin Resistance Atherosclerosis Family Study (IRAS-FS) for association with quantitative measures of glucose homeostasis and determine their biological role in vivo. RESEARCH DESIGN AND METHODS: Seventeen type 2 diabetes-associated single nucleotide...
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