Article
TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study.
Diabetes - 1 Nov 2006
Cauchi Stéphane, Meyre David, Choquet Hélène, Dina Christian, Born Catherine, Marre Michel, Balkau Beverley, Froguel Philippe
Abstract excerpt
Recently, case-control studies demonstrated that a TCF7L2 (transcription factor 7-like 2 gene) noncoding variant (rs7903146 T at-risk allele) was strongly associated with an increased risk of type 2 diabetes. However, the predictive value of this marker in a nonselected general population remains unknown. In this study, our aim was to assess the contribution of this variant to the prevalence and incidence of...
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