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Article

Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent.

Diabetologia - 1 Aug 2007

Elbein S C, Chu W S, Das S K, Yao-Borengasser A, Hasstedt S J, Wang H, Rasouli N, Kern P A

Abstract excerpt

AIMS/HYPOTHESIS: We sought to determine: (1) the role of previously described transcription factor 7-like 2 (TCF7L2) variants in type 2 diabetes in African American individuals and in participants of European ancestry; (2) the physiological impact of these variants on glucose homeostasis; and (3) whether the non-coding variants altered TCF7L2 expression in adipocytes and transformed lymphocytes. METHODS:...

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PMID: 17579832
DOI: 10.1007/s00125-007-0717-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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