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Article

Role of the PLDLS-binding cleft region of CtBP1 in recruitment of core and auxiliary components of the corepressor complex.

Molecular and cellular biology - 1 Jan 2008

Kuppuswamy M, Vijayalingam S, Zhao Ling-Jun, Zhou Yun, Subramanian T, Ryerse Jan, Chinnadurai G

Abstract excerpt

C-terminal binding protein (CtBP) family proteins CtBP1 and CtBP2 are highly homologous transcriptional corepressors and are recruited by a large number of transcription factors to mediate sequence-specific transcriptional repression. In addition to DNA-binding repressors, the nuclear protein complex of CtBP1 consists of enzymatic constituents such as histone deacetylases (HDAC1/2), histone methyl transferases...

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Source

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Identifiers

PMID: 17967884
DOI: 10.1128/MCB.01077-07
PMCID: PMC2223311

Genes

HDAC1
CDYL
PIAS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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