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Article

The frequency of an IL-18-associated haplotype in Africans.

European journal of human genetics : EJHG - 1 Apr 2013

Thompson Simon R, Humphries Steve E, Thomas Mark G, Ekong Rosemary, Tarekegn Ayele, Bekele Endeshaw, Creemer Olivia, Bradman Neil, Veeramah Krishna R

Abstract excerpt

Variation within the gene for the proinflammatory cytokine interleukin (IL)-18 has been associated with inter-individual differences in levels of free protein and disease risk. We investigated the frequency of function-associated IL18 gene haplotypes in an extensive sample (n=2357) of African populations from across the continent. A previously identified five tagging SNP (single-nucleotide polymorphism) haplotype...

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Identifiers

PMID: 22929027
DOI: 10.1038/ejhg.2012.184
PMCID: PMC3598319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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