Article
Association of IL-18 gene polymorphisms with clinical aspects of hyperlipidemia in middle-aged and early people in the community.
International journal of medical sciences - 1 Jan 2024
Chen Po-Chun, Chen Wei-Hung, Lien Li-Ming, Chou Chia-Chi, Chao Chia-Chia, Bai Chyi-Huey
Abstract excerpt
Hyperlipidemia is notorious for causing coronary artery disease (CAD). IL-18 is a proinflammtory cytokine that contributes to the pathogenesis of CAD. Previous reports have revealed that genetic polymorphism of IL-18 is associated with its expression level as well as the susceptibility to CAD. In the present study, we aim to investigate the relationship between IL-18 single nucleotide polymorphisms (SNPs) and...
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