Article
Genetic variation within IL18 is associated with insulin levels, insulin resistance and postprandial measures.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jul 2011
Smart M C, Dedoussis G, Yiannakouris N, Grisoni M L, Ken-Dror G, Yannakoulia M, Papoutsakis C, Louizou E, Mantzoros C S, Melistas L, Kontogianni M D, Cooper J A, Humphries S E, Talmud P J
Abstract excerpt
BACKGROUND AND AIMS: IL-18 expression is up-regulated in atherosclerotic plaques, and higher levels are seen in obese and Type 2 Diabetic individuals. More recently, a possible role for IL-18 in glucose and energy homeostasis has been suggested. METHODS AND RESULTS: We investigated variation within the IL18 gene and its association with measures of obesity and the metabolic syndrome. Five IL18 tagging single...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.