Article
Interleukin-17A gene haplotypes are associated with risk of premature coronary artery disease in Mexican patients from the Genetics of Atherosclerotic Disease (GEA) study.
PloS one - 1 Jan 2015
Vargas-Alarcón Gilberto, Angeles-Martínez Javier, Villarreal-Molina Teresa, Alvarez-León Edith, Posadas-Sánchez Rosalinda, Cardoso-Saldaña Guillermo, Ramírez-Bello Julian, Pérez-Hernández Nonanzit, Juárez-Rojas Juan Gabriel, Rodríguez-Pérez José Manuel, Fragoso José Manuel, Posadas-Romero Carlos
Abstract excerpt
AIM: The role of interleukin 17A (IL-17A) in the inflammatory process has caused interest in the potential significance of IL-17A as a biomarker for coronary artery disease (CAD). The aim of the present study was to evaluate the role of IL-17A gene polymorphisms as susceptibility markers for CAD in the Mexican population. METHODS: Four IL-17A gene polymorphisms (rs8193036, rs3819024, rs2275913 and rs8193037) were...