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Article

TRESK two-pore-domain K+ channels constitute a significant component of background potassium currents in murine dorsal root ganglion neurones.

The Journal of physiology - 15 Dec 2007

Dobler Tina, Springauf Andreas, Tovornik Stefanie, Weber Maruschka, Schmitt Angelika, Sedlmeier Reinhard, Wischmeyer Erhard, Döring Frank

Abstract excerpt

TRESK (TWIK-related spinal cord K(+) channel) is the most recently identified member of the two-pore-domain potassium channel (K(2P)) family, the molecular source of background potassium currents. Human TRESK channels are not affected by external acidification. However, the mouse orthologue displays moderate pH dependence isolated to a single histidine residue adjacent to the GYG selectivity filter. In the human...

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Identifiers

PMID: 17962323
DOI: 10.1113/jphysiol.2007.145649
PMCID: PMC2375503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TRESK two-pore-domain K+ channels constitute a significant component of background potassium currents in murine dorsal root ganglion neurones.PMID 17962323Read ↗

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