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Article

Zinc and mercuric ions distinguish TRESK from the other two-pore-domain K+ channels.

Molecular pharmacology - 1 Mar 2006

Czirják Gábor, Enyedi Péter

Abstract excerpt

TWIK-related spinal cord K+ channel (TRESK) is the most recently cloned two-pore-domain potassium (2PK+) channel, regulated by the calcium/calmodulin-dependent protein phosphatase calcineurin. Functional identification of endogenous TRESK and its distinction from the other 2PK+ channels, producing similar background K+ current, are impeded by the lack of specific inhibitors. Therefore, we searched for antagonists...

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Identifiers

PMID: 16354767
DOI: 10.1124/mol.105.018556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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