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Article

Critical contribution of the intracellular C-terminal region to TRESK channel activity is revealed by the epithelial Na+ current ratio method.

The Journal of biological chemistry - 1 Jun 2023

Debreczeni Dorina, Baukál Dóra, Pergel Enikő, Veres Irén, Czirják Gábor

Abstract excerpt

TRESK (K2P18.1) possesses unique structural proportions within the K2P background potassium channel family. The previously described TRESK regulatory mechanisms are based on the long intracellular loop between the second and the third transmembrane segments (TMS). However, the functional significance of the exceptionally short intracellular C-terminal region (iCtr) following the fourth TMS has not yet been...

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Identifiers

PMID: 37084812
DOI: 10.1016/j.jbc.2023.104737
PMCID: PMC10206819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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