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Article

Efficient algorithms for genome-wide tagSNP selection across populations via the linkage disequilibrium criterion.

Computational systems bioinformatics. Computational Systems Bioinformatics Conference - 1 Jan 2007

Liu Lan, Wu Yonghui, Lonardi Stefano, Jiang Tao

Abstract excerpt

In this paper, we study the tagSNP selection problem on multiple populations using the pairwise r(2) linkage disequilibrium criterion. We propose a novel combinatorial optimization model for the tagSNP selection problem, called the minimum common tagSNP selection (MCTS) problem, and present efficient solutions for MCTS. Our approach consists of three main steps including (i) partitioning the SNP markers into...

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PMID: 17951813

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