TagSNP selection based on pairwise LD criteria and power analysis in association studies.

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Article

TagSNP selection based on pairwise LD criteria and power analysis in association studies.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2006

Gopalakrishnan Shyam, Qin Zhaohui S

Abstract excerpt

TagSNP selection is an important step in designing case control association studies. Among selection methods that have proliferated, the ones based on pairwise LD measurement are attractive for the purpose of designing association studies. The goal is to minimize the number of markers selected for genotyping in a particular platform and therefore reduce genotyping cost while simultaneously representing...

Topics

Algorithms
Computational Biology
Databases, Nucleic Acid
Genome, Human
Humans
Linkage Disequilibrium
Polymorphism, Single Nucleotide
Software

Source

Open in PubMed

Identifiers

PMID: 17094265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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