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Article

dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity data.

Bioinformatics (Oxford, England) - 22 May 2004

Lin Ming, Wei Lee-Jen, Sellers William R, Lieberfarb Marshall, Wong Wing Hung, Li Cheng

Abstract excerpt

MOTIVATION: Oligonucleotide microarrays allow genotyping of thousands of single-nucleotide polymorphisms (SNPs) in parallel. Recently, this technology has been applied to loss-of-heterozygosity (LOH) analysis of paired normal and tumor samples. However, methods and software for analyzing such data are not fully developed. RESULT: Here, we report automated methods for pooling SNP array replicates to make LOH...

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Identifiers

PMID: 14871870
DOI: 10.1093/bioinformatics/bth069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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