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Article

TP53 codon 72 polymorphism as a risk factor for cardiovascular disease in a Brazilian population.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Nov 2007

Smith M A C, Silva M D A, Cendoroglo M S, Ramos L R, Araujo L M Q, Labio R W, Burbano R R, Chen E S, Payão S L M

Abstract excerpt

TP53, a tumor suppressor gene, has a critical role in cell cycle, apoptosis and cell senescence and participates in many crucial physiological and pathological processes. Identification of TP53 polymorphism in older people and age-related diseases may provide an understanding of its physiology and pathophysiological role as well as risk factors for complex diseases. TP53 codon 72 (TP53:72) polymorphism was...

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PMID: 17934643
DOI: 10.1590/s0100-879x2007001100007

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