Article
TP53 codon 72 polymorphism and type 2 diabetes: a case-control study in South Indian population.
Molecular biology reports - 1 Jun 2021
Punja Harshitha K, Nanjappa Dechamma Pandyanda, Babu Nishith, Kalladka Krithika, Shanti Priya Dias B, Chakraborty Gunimala, Rao Sudhindra M, Chakraborty Anirban
Abstract excerpt
TP53 functions primarily as a tumor suppressor, controlling a myriad of signalling pathways that prevent a cell from undergoing malignant transformation. This tumor suppressive function requires an activation and stabilization of TP53 in response to cell stressors. However, besides its cancer-preventive functions, TP53 is also known to be involved in diverse cellular processes including metabolism, reproduction,...
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