Article
Analysis of p53 gene polymorphism (codon 72) in symptomatic patients with atherosclerosis.
Genetics and molecular research : GMR - 17 Aug 2017
Lagares M H, Silva K S F, Barbosa A M, Rodrigues D A, Costa I R, Martins J V M, Morais M P, Campedelli F L, Moura K K V O
Abstract excerpt
Atherosclerosis is a multifactorial pathological disease that alters the morphology and function of arterial walls. The atheroma growth leads to vessel hardening and lumen narrowing, limiting the blood flow. The atheroma plaque can eventually break, expose highly thrombogenic material and lead to platelet activation and subsequent formation of a thrombus that may block blood flow in loco, or even leading to...
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