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Article

Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease.

Brain : a journal of neurology - 1 Nov 2007

Pike Kerryn E, Savage Greg, Villemagne Victor L, Ng Steven, Moss Simon A, Maruff Paul, Mathis Chester A, Klunk William E, Masters Colin L, Rowe Christopher C

Abstract excerpt

Beta-amyloid (Abeta) deposition is pathognomic for Alzheimer's disease (AD), but may occur in normal elderly people without apparent cognitive effect. Episodic memory impairment is an early and prominent sign of AD, but its relationship with Abeta burden in non-demented persons and in AD patients is unclear. We examined this relationship using 11C-PIB-PET as a quantitative marker of Abeta burden in vivo in...

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PMID: 17928318
DOI: 10.1093/brain/awm238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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