Article
Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer's disease.
Brain : a journal of neurology - 1 Jan 2014
Lim Yen Ying, Maruff Paul, Pietrzak Robert H, Ames David, Ellis Kathryn A, Harrington Karra, Lautenschlager Nicola T, Szoeke Cassandra, Martins Ralph N, Masters Colin L, Villemagne Victor L, Rowe Christopher C
Abstract excerpt
High amyloid has been associated with substantial episodic memory decline over 18 and 36 months in healthy older adults and individuals with mild cognitive impairment. However, the nature and magnitude of amyloid-related memory and non-memory change from the preclinical to the clinical stages of Alzheimer's disease has not been evaluated over the same time interval. Healthy older adults (n = 320), individuals...
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