Article
Indicators of amyloid burden in a population-based study of cognitively normal elderly.
Neurology - 9 Oct 2012
Mielke Michelle M, Wiste Heather J, Weigand Stephen D, Knopman David S, Lowe Val J, Roberts Rosebud O, Geda Yonas E, Swenson-Dravis Dana M, Boeve Bradley F, Senjem Matthew L, Vemuri Prashanthi, Petersen Ronald C, Jack Clifford R
Abstract excerpt
OBJECTIVES: Secondary prevention trials in subjects with preclinical Alzheimer disease may require documentation of brain amyloidosis. The identification of inexpensive and noninvasive screening variables that can identify individuals who have significant amyloid accumulation would reduce screening costs. METHODS: A total of 483 cognitively normal (CN) individuals, aged 70-92 years, from the population-based Mayo...
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