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Article

APOE modifies the association between Aβ load and cognition in cognitively normal older adults.

Neurology - 24 Jan 2012

Kantarci K, Lowe V, Przybelski S A, Weigand S D, Senjem M L, Ivnik R J, Preboske G M, Roberts R, Geda Y E, Boeve B F, Knopman D S, Petersen R C, Jack C R

Abstract excerpt

OBJECTIVE: To determine the relationship between β-amyloid (Aβ) load as measured by [(11)C]-Pittsburgh compound B (PiB) PET and cognitive function in cognitively normal older adults. METHODS: We studied 408 cognitively normal older adults who participated in the population-based Mayo Clinic Study of Aging (MCSA) from January 2009 through March 2011. The participants underwent PiB PET and neuropsychometric testing...

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Share to Amyloid beta-Peptides
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22189452
DOI: 10.1212/WNL.0b013e31824365ab
PMCID: PMC3280056

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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