Major histocompatibility complex class II and<i>BTNL2</i>associations in sarcoidosis

Abstract excerpt

To the Editor: Sarcoidosis is a multiple organ immune-mediated disease of unknown aetiology. Identified genetic risk factors within the major histocompatibility complex (MHC), such as butyrophilin-like ( BTNL)2 , human leukocyte antigen ( HLA)-DRB1*03 and HLA-DRB1*15 , and protective factors, such as HLA-DRB1*01 , are found in many populations [1, 2]. The vast majority of sarcoidosis patients have a favourable...

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