Article
[Study on gene control region of mitochondrial DNA in familial breast cancer].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2007
Zhou Yun-li, Niu Rui-fang, Shi Yu-rong
Abstract excerpt
OBJECTIVE: To study on mutations in D-loop region which is gene control region of mitochondrial genome in patients with familial breast cancer. METHODS: Twenty-three breast cancer patients came from twenty-one families of breast cancer, and eighteen healthy controls participated in the study. PCR amplification of D-loop region in mitochondrial DNA was performed and then the product was sequenced to analyze...
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