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Article

Mitochondrial DNA variants and risk of familial breast cancer: an exploratory study.

International journal of oncology - 1 May 2014

Tommasi Stefania, Favia Paola, Weigl Stefania, Bianco Angelica, Pilato Brunella, Russo Luciana, Paradiso Angelo, Petruzzella Vittoria

Abstract excerpt

To assess if mitochondrial DNA (mtDNA) variants are associated with mutations in BRCA susceptibility genes and to investigate the possible role of mitochondrial alterations as susceptibility markers in familial breast cancer (BC), 22 patients with or without BRCA1/BRCA2 mutations, 14 sporadic BC patients and 20 healthy subjects were analyzed. In the D-loop and in the MTND4 region, variants significantly...

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Share to BRCA1 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to NADH Dehydrogenase

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Source

Identifiers

PMID: 24603941
DOI: 10.3892/ijo.2014.2324

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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