Article
Evaluating mitochondrial DNA in patients with breast cancer and benign breast disease.
Journal of cancer research and clinical oncology - 1 Apr 2011
Shen Lijun, Wei Jia, Chen Tao, He Jing, Qu Jianchun, He Xiumei, Jiang Luxi, Qu Yemin, Fang Hezhi, Chen Guorong, Lu Jianxin, Bai Yidong
Abstract excerpt
PURPOSE: To evaluate the role of mtDNA in breast cancer. METHODS: We carried out an investigation into the mtDNA major control region or D-loop region and an essential and the largest mtDNA protein-coding gene, NADH dehydrogenase subunit 5 (ND5), together with a mitochondrial haplogroup analysis in 64 patients with breast cancer (BC) and 54 patients with benign breast disease (BBD) as controls. RESULTS: Mutations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
