Article
[Correlation of breast tumor pathogenesis and somatic mutations on the basis of mitochondrial DNA whole genome].
Zhonghua yi xue za zhi - 12 Apr 2011
Yang Yue, He Jun-dong, Guo Xue-jun, Che Yan-hua, Zhang Yong, Li Li
Abstract excerpt
OBJECTIVE: To investigate the correlation of somatic mutations in whole genome of mitochondrial DNA (mtDNA) in patients with breast tumor. METHODS: The DNA of tumor tissue and peripheral blood in 4 benign breast tumor patients from August 2009 to December 2009 in our hospital were extracted. The mtDNA whole genomes were amplified by polymerase chain reaction (PCR) and the mutations of products screened by...
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