Article
[Roles of mitochondrial DNA somatic mutations in the pathogenesis of benign breast disease: a perspective from whole genome study].
Zhonghua yi xue za zhi - 11 Sept 2012
Yang Yue, Mei Shuo, He Jun-dong, Guo Xue-jun, Che Yan-hua, Zhang Yong, Li Li
Abstract excerpt
OBJECTIVE: To explore the potential roles of mitochondrial DNA somatic mutations in benign breast disease based on the entire genome of mitochondrial DNA and elucidate the relationship between benign breast disease and breast cancer. METHODS: The genomic DNA of tumor tissue and peripheral blood in 28 benign breast disease patients with an average age of 33 years (range: 30 - 50) were extracted respectively....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.