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Mutation screening in the mitochondrial D-loop region of tumoral and non-tumoral breast cancer in Iranian patients.

Acta medica Iranica - 1 Jan 2012

Rahmani Babak, Azimi Cyrus, Omranipour Ramesh, Raoofian Reza, Zendehdel Kazem, Saee-Rad Samira, Heidari Mansour

Abstract excerpt

The mitochondrial DNA (mtDNA) mutations in mitochondrial coding and non coding regions seem to be important in carcinogenesis. The aim of this investigation was to evaluate coding region (mt-tRNA(Phe) and tRNA(Pro)) and non-coding sequence, mitochondrial displacement loop (mtDNA D-loop), in the cancerous and non-cancerous lesions of Iranian patients with breast cancer (BC). Genomic DNA was extracted from 50...

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PMID: 22930374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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