Article
[An analysis method to apply linkage disequilibrium maps to association study].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2007
Hu Cheng, Jia Wei-ping, Wang Cong-rong, Zhang Rong, Ma Xiao-jing, Fang Qi-chen, Xiang Kun-san
Abstract excerpt
OBJECTIVE: To apply linkage disequilibrium (LD) maps to associations studies with high throughput single nucleotide polymorphisms (SNPs). METHODS: Seven hundred and fifty-four SNPs were genotyped in 160 Shanghai Chinese. LD maps were constructed in cases and controls separately. By comparing the decline of LD unit with distance between the two groups, disease susceptible loci were estimated. This method was...
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