Article
Brief and long maternal separations decrease corticosterone secretion in a lupus-prone strain: dissociation from disease-related parameters.
Brain, behavior, and immunity - 1 Mar 2008
Catallani Bruna, Palma Beatriz Duarte, Gil Frida Zaladek, Suchecki Deborah
Abstract excerpt
Neonatal manipulations are known to alter the activity of the immune system and the hypothalamus-pituitary-adrenal (HPA) axis. This study was performed in order to examine whether brief and long maternal separations (BMS and LMS, respectively) interfere with the onset and development of murine lupus in NZB/NZWF1 females, and to determine whether the pattern of corticosterone (CORT) secretion throughout life is...
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