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Article

Anxiety behavior, exploratory behavior, and activity in NZB x NZW F1 hybrid mice: role of genotype and autoimmune disease progression.

Brain, behavior, and immunity - 1 Sept 1996

Schrott L M, Crnic L S

Abstract excerpt

Behavioral changes often accompany the autoimmune disease systemic lupus erythematosus (SLE) in humans and animals. In a mouse model of SLE, the NZB x NZW F1 (B/W) hybrid, 12-week-old mice display more anxiety behavior, less activity, and less exploratory behavior than non-autoimmune female NZW m...

Topics

Aging
Animals
Anxiety
Autoimmune Diseases
Exploratory Behavior
Female
Genotype
Hybridization, Genetic
Immunoglobulin G
Immunoglobulin M
Lupus Erythematosus, Systemic
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred NZB

Motor Activity

Pregnancy

Source

Identifiers

PMID: 8954598
DOI: 10.1006/brbi.1996.0023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8954598-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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