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Article

Genetic variation in the stress response: susceptibility to experimental allergic encephalomyelitis and implications for human inflammatory disease.

Immunology today - 1 Feb 1991

Mason D

Abstract excerpt

Glucocorticoids that are released from the adrenal glands in response to stress can have profound effects on the immune system. Here, Don Mason illustrates how genetic variation in the magnitude of such a response can determine susceptibility to an experimental autoimmune disease in rats and discusses the implications for susceptibility to inflammatory diseases in humans. He also addresses the possible long-term...

Topics

Animals
Antibody Formation
Autoimmune Diseases
Encephalomyelitis, Autoimmune, Experimental
Genetic Predisposition to Disease
Glucocorticoids
Humans
Immune Tolerance
Immunity, Cellular
Infections
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neuroimmunomodulation

Rats

Stress, Physiological

Source

Identifiers

PMID: 2059305
DOI: 10.1016/0167-5699(91)90158-P

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2059305-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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