Article
Effect of an exogenous trigger on the pathogenesis of lupus in (NZB x NZW)F1 mice.
Arthritis and rheumatism - 1 Aug 2002
Yoshida Hideo, Satoh Minoru, Behney Krista M, Lee Chee-Gun, Richards Hanno B, Shaheen Victoria M, Yang Jun-Qi, Singh Ram R, Reeves Westley H
Abstract excerpt
OBJECTIVE: This study examined the interactions between exogenous and endogenous factors shaping the phenotype of lupus in autoimmune (NZB x NZW)F(1) mice exposed to pristane, a model environmental trigger. METHODS: Frequencies of various autoantibodies in untreated NZB/NZW mice were determined by various means (immunoprecipitation, enzyme-linked immunosorbent assay [ELISA], Crithidia luciliae kinetoplast...
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