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Article

Silica accelerated systemic autoimmune disease in lupus-prone New Zealand mixed mice.

Clinical and experimental immunology - 1 Mar 2003

Brown J M, Archer A J, Pfau J C, Holian A

Abstract excerpt

The genetic backgrounds of lupus-prone murine models are a valuable resource for studying the influence of environmental exposure on autoimmune diseases in sensitive populations. Epidemiological studies have shown associations between silica exposure and several autoimmune diseases, including scleroderma and systemic lupus erythematosus. To determine whether silica exposure can exacerbate systemic autoimmunity in...

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Identifiers

PMID: 12605693
DOI: 10.1046/j.1365-2249.2003.02094.x
PMCID: PMC1808650

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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