Article
Function of the hypothalamo-pituitary-adrenal axis and humoral immune mechanisms during experimental allergic encephalomyelitis in SJL/J mice.
Neuroimmunomodulation - 1 Jan 2002
Andreini Isabella, Getuli Claudia, Pacelli Vanessa, Manno Rosanna, Ragazzoni Enzo, Nunziata Alfredo, Navarra Pierluigi
Abstract excerpt
OBJECTIVES: In the present work, a method to induce experimental allergic encephalomyelitis (EAE) in female SJL/J mice was developed and validated in our laboratory. Although the latter is a popular animal model to mimic human multiple sclerosis, it remains to be clarified if: (1) the measurement of circulating antibodies against myelin antigens can be used as an index to predict the development of clinical EAE,...
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