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Article

Within-lifetime trade-offs but evolutionary freedom for hormonal and immunological traits: evidence from mice bred for high voluntary exercise.

The Journal of experimental biology - 15 May 2012

Downs Cynthia J, Schutz Heidi, Meek Thomas H, Dlugosz Elizabeth M, Acosta Wendy, de Wolski Karen S, Malisch Jessica L, Hayes Jack P, Garland Theodore

Abstract excerpt

Chronic increases in circulating corticosterone (CORT) generally suppress immune function, but it is not known whether evolved increases necessarily have similar adverse effects. Moreover, the evolution of immune function might be constrained by the sharing of signaling molecules, such as CORT, across numerous physiological systems. Laboratory house mice (Mus domesticus Linnaeus) from four replicate lines...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22539732
DOI: 10.1242/jeb.066167

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CORT

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