Article
A polymorphism in CD14 modifies the effect of farm milk consumption on allergic diseases and CD14 gene expression.
The Journal of allergy and clinical immunology - 1 Dec 2007
Bieli Christian, Eder Waltraud, Frei Remo, Braun-Fahrländer Charlotte, Klimecki Walt, Waser Marco, Riedler Josef, von Mutius Erika, Scheynius Annika, Pershagen Göran, Doekes Gert, Lauener Roger, Martinez Fernando D
Abstract excerpt
BACKGROUND: Consumption of farm milk in early life is associated with less asthma and allergies. OBJECTIVE: We hypothesized that genetic variation in the innate immunity receptor CD14 might modify the association between farm milk consumption and asthma and atopy. METHODS: Questionnaire data, serum IgE levels, and genotypes for 4 single nucleotide polymorphisms in CD14 were assessed in farmers' and nonfarmers'...
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