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Article

CD14 promoter polymorphisms in atopic families: implications for modulated allergen-specific immunoglobulin E and G1 responses.

International archives of allergy and immunology - 1 Jan 2006

Jackola Duaine R, Basu Saonli, Liebeler Carol L, Willaert Rebecca, Luah San-San, Oetting William, King Richard A, Blumenthal Malcolm N

Abstract excerpt

BACKGROUND: CD14 promoter DNA sequence polymorphisms for the endotoxin receptor gene have been implicated in modulating allergen-specific immunoglobulin (Ig)E responses in randomly selected individuals with atopy. We sought to determine if a single nucleotide polymorphism in the CD14 promoter region is associated with atopy in atopic families, and to assess its influence on serum levels of CD14 and...

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Identifiers

PMID: 16446545
DOI: 10.1159/000091167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CD14 promoter polymorphisms in atopic families: implications for modulated allergen-specific immunoglobulin E and G1 responses.PMID 16446545Read ↗

Association between CD14 polymorphisms and serum soluble CD14 levels: effect of atopy and endotoxin inhalation.Semantic proximity Read ↗

A promoter polymorphism in the CD14 gene is associated with elevated levels of soluble CD14 but not with IgE or atopic diseases.Semantic proximity Read ↗

Association of a promoter polymorphism of the CD14 gene and atopy.Semantic proximity Read ↗

A Polymorphism* in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E.Semantic proximity Read ↗

CD14, endotoxin, and asthma risk: actions and interactions.Semantic proximity Read ↗

Two CD14 promoter polymorphisms and atopic phenotypes in Czech patients with IgE-mediated allergy.Semantic proximity Read ↗

A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity.Semantic proximity Read ↗

A polymorphism in CD14 modifies the effect of farm milk consumption on allergic diseases and CD14 gene expression.Semantic proximity Read ↗

The functional genomics of CD14 and its role in IgE responses: an integrated view.Semantic proximity Read ↗

Evaluation of the CD14 C-159 T polymorphism in the German Multicenter Allergy Study cohort.Semantic proximity Read ↗

The differential effect of genetic variation on soluble CD14 levels in human plasma and milk.Semantic proximity Read ↗

CD14 promoter polymorphisms have no functional significance and are not associated with atopic phenotypes.Semantic proximity Read ↗

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