Article
The -159 C-->T polymorphism of CD14 is associated with nonatopic asthma and food allergy.
The Journal of allergy and clinical immunology - 1 Aug 2003
Woo Jessica G, Assa'ad Amal, Heizer Angela B, Bernstein Jonathan A, Hershey Gurjit K Khurana
Abstract excerpt
BACKGROUND: CD14, the receptor for LPS, plays an important role in innate immunity. A polymorphism in the promotor for CD14, -159 C-->T, has been implicated in atopy. OBJECTIVE: We explored the relationship of this polymorphism with both atopic and nonatopic asthma, as well as with food allergy. METHODS: Patients with asthma and food allergy were recruited along with nonatopic, nonasthmatic control subjects. The...
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