Article
Pet keeping and tobacco exposure influence CD14 methylation in childhood.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Dec 2012
Munthe-Kaas Monica Cheng, Bertelsen Randi J, Torjussen Tale Maehre, Hjorthaug Hanne Sagsveen, Undlien Dag E, Lyle Robert, Gervin Kristina, Granum Berit, Mowinckel Petter, Carlsen Kai Håkon, Carlsen Karin C Lødrup
Abstract excerpt
BACKGROUND: Several CD14 gene-environment interactions in relation to the development of allergic diseases have been reported, but the underlying biological mechanisms are unclear. We recently showed that CD14 methylation increased during childhood, parallelling a decreased impact of CD14 polymorphisms on soluble CD14 levels. Here, we aim to explore whether environmental stimuli during childhood affects CD14...
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