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Article

Prenatal and early-life exposures alter expression of innate immunity genes: the PASTURE cohort study.

The Journal of allergy and clinical immunology - 1 Aug 2012

Loss Georg, Bitter Sondhja, Wohlgensinger Johanna, Frei Remo, Roduit Caroline, Genuneit Jon, Pekkanen Juha, Roponen Marjut, Hirvonen Maija-Riitta, Dalphin Jean-Charles, Dalphin Marie-Laure, Riedler Josef, von Mutius Erika, Weber Juliane, Kabesch Michael, Michel Sven, Braun-Fahrländer Charlotte, Lauener Roger

Abstract excerpt

BACKGROUND: There is evidence that gene expression of innate immunity receptors is upregulated by farming-related exposures. OBJECTIVE: We sought to determine environmental and nutritional exposures associated with the gene expression of innate immunity receptors during pregnancy and the first year of a child's life. METHODS: For the Protection Against Allergy: Study in Rural Environments (PASTURE) birth cohort...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22846753
DOI: 10.1016/j.jaci.2012.05.049

Genes

TLR4
TLR5
TLR6
TLR7
TLR8
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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