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Article

Atopy and new-onset asthma in young Danish farmers and CD14, TLR2, and TLR4 genetic polymorphisms: a nested case-control study.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Nov 2007

Smit L A M, Bongers S I M, Ruven H J T, Rijkers G T, Wouters I M, Heederik D, Omland Ø, Sigsgaard T

Abstract excerpt

BACKGROUND: Evidence exists that exposure to high levels of microbial agents such as endotoxin in the farm environment decreases the risk of atopic sensitization. Genetic variation in innate immunity genes may modulate the response to microbial agents and thus influence susceptibility to asthma and atopy. OBJECTIVE: To study potential associations between single nucleotide polymorphisms (SNPs) in CD14, Toll-like...

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Source

Identifiers

PMID: 17877764
DOI: 10.1111/j.1365-2222.2007.02831.x

Genes

TLR2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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