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Article

Endotoxin exposure, CD14 and wheeze among farmers: a gene--environment interaction.

Occupational and environmental medicine - 1 Nov 2011

Smit Lidwien A M, Heederik Dick, Doekes Gert, Koppelman Gerard H, Bottema Renske W B, Postma Dirkje S, Wouters Inge M

Abstract excerpt

OBJECTIVES: Endotoxin-exposed workers are at an increased risk of non-atopic asthma and lung-function decline. Genetic variants may influence susceptibility to these effects. The objective of the present study was to assess whether the association between occupational endotoxin exposure and wheeze is modified by innate immunity gene variants. METHODS: Twenty-four single nucleotide polymorphisms (SNPs) in CD14,...

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Source

Identifiers

PMID: 21389010
DOI: 10.1136/oem.2010.060038

Genes

TLR2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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