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Article

Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons.

Development (Cambridge, England) - 1 Nov 2007

Hack Iris, Hellwig Sabine, Junghans Dirk, Brunne Bianka, Bock Hans H, Zhao Shanting, Frotscher Michael

Abstract excerpt

Reelin, its lipoprotein receptors [very low density lipoprotein receptor (Vldlr) and apolipoprotein E receptor 2 (ApoER2; also known as Lrp8)], and the cytoplasmic adaptor protein disabled 1 (Dab1) are important for the correct formation of layers in the cerebral cortex. Reeler mice lacking the reelin protein show altered radial neuronal migration resulting in an inversion of cortical layers. ApoER2 Vldlr...

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Source

Identifiers

PMID: 17913789
DOI: 10.1242/dev.005447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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