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Article

Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration.

Nature - 21 Apr 2011

Sentürk Aycan, Pfennig Sylvia, Weiss Alexander, Burk Katja, Acker-Palmer Amparo

Abstract excerpt

Coordinated migration of neurons in the developing and adult brain is essential for its proper function. The secreted glycoprotein Reelin (also known as RELN) guides migration of neurons by binding to two lipoprotein receptors, the very-low-density lipoprotein receptor (VLDLR) and apolipoprotein E receptor 2 (ApoER2, also known as LRP8). Loss of Reelin function in humans results in the severe developmental...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21460838
DOI: 10.1038/nature09874

Genes

VLDLR
LRP8
RELN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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